Parent supplement
- Zincentity:supplement:zinc
Ingredient intelligence · non-production preview
Zinc gluconate
Identity structure
Parent and form relationships
Ingredients, supplement concepts, supplement-form projections, and commercial products remain separate records.Related ingredient forms
- Zinc citratemineral compound
Origin is not a quality score
Origin classification is not assigned for this pilot. MEDucated does not rank naturally occurring or manufactured ingredients as better or worse based on origin.
Evidence availability
Direct ingredient evidence boundaries
Supplement-level evidence is reused only when a frozen source block explicitly names this ingredient or form. Missing topics remain unavailable.Identity and what it is
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Common uses
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Biological role
Direct source evidence for this ingredient topic is not yet available in MEDucated.
What evidence has studied
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Potential benefits studied
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Safety considerations
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Side effects
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Medication interactions
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Supplement interactions
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Food interactions
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Forms and chemical variants
A frozen NIH ODS source explicitly identifies this ingredient or form. Source wording is preserved without creating a new conclusion.
Structural characterization
Evidence profile
- Evidence source
- NIH ODS evidence synthesis
- Linked references
- 7 identified
- Human evidence
- Human evidence identified
- Randomized trials
- Randomized trials not identified in the frozen metadata
- Reviews and meta-analyses
- Systematic reviews or meta-analyses not identified in the frozen metadata
- Evidence recency
- 1986–2021
- Source-described consistency
- Not characterized in these source blocks
- MEDucated evidence rating
- Not assigned
Reference counts describe frozen source associations; a larger count does not establish stronger evidence.
Inspect technical evidence details
Evidence types identified
- Study type could not be determined7
Source-described limitations
No explicit limitation phrase was identified in these imported source blocks.
Classified references
Office of Dietary Supplements, National Institutes of Health. Dietary Supplement Label Database. 2021.
Study type could not be determined · Population basis: unknown · Directness: not assessedBrnic M, Wegmuller R, Melse-Boonstra A, Stomph T, Zeder C, Tay FM, et al. Zinc absorption by adults is similar from intrinsically labeled zinc- biofortified rice and from rice fortified with labeled zinc sulfate. J Nutr 2016;146:76-80. [PubMed abstract]
Study type could not be determined · Population basis: human · Directness: not assessedWegmuller R, Tay F, Zeder C, Brnic M, Hurrell RF. Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide. J Nutr 2014;144:132-6. [PubMed abstract]
Study type could not be determined · Population basis: human · Directness: not assessedSolomons NW. Competitive interaction of iron and zinc in the diet: consequences for human nutrition. J Nutr 1986;116:927-35. [PubMed abstract]
Study type could not be determined · Population basis: human · Directness: not assessedWhittaker P. Iron and zinc interactions in humans. Am J Clin Nutr 1998;68:442s-6s. [PubMed abstract]
Study type could not be determined · Population basis: human · Directness: not assessedEuropean Food Safety Authority. Scientific Opinion on Dietary Reference Values for zinc. 2014.
Study type could not be determined · Population basis: unknown · Directness: not assessedArredondo M, Martínez R, Núñez MT, Ruz M, Olivares M. Inhibition of iron and copper uptake by iron, copper and zinc. Biol Res 2006;39:95-102. [PubMed abstract]
Study type could not be determined · Population basis: unknown · Directness: not assessed
Read imported source wording
Forms of zinc that are commonly found in dietary supplements include zinc sulfate, zinc acetate, and zinc gluconate. Taking supplements that contain a substantial amount of iron (≥25 mg) at the same time as zinc supplements can reduce zinc absorption and plasma concentrations of zinc.
Zinc is available in supplements that only contain zinc, supplements that contain zinc in combination with other ingredients, and in many multivitamin/mineral products [13]. Supplements can contain any of a variety of forms of zinc, including zinc sulfate, zinc acetate, and zinc gluconate [14]. The Supplement Facts panel on a dietary supplement label declares the amount of elemental zinc in the product, not the weight of the entire zinc-containing compound.
Absorption of zinc from supplements that contain zinc citrate or zinc gluconate is similar, at approximately 61% in young adults; the absorption from supplements that contain zinc oxide is 50% [15]. Taking supplements containing 25 mg elemental iron or more at the same time as zinc supplements can reduce zinc absorption and plasma zinc concentrations [16-19]. However, the iron added to enriched or fortified foods does not significantly interfere with zinc absorption because the chemical form of iron used in fortification is typically poorly soluble in the gut and does not compete strongly with zinc for absorpion.
Where did MEDucated get this?
Zinc
- Publisher
- NIH Office of Dietary Supplements
- Revision
- January 6, 2026
- Source fingerprint
- e2f6aba81491596341956f3feef8ef8fbf86c5d47bd9573d1df5ad20dd791ffe
- Source blocks
- ingredient-block:zinc-gluconate:ods-block:zinc-health-professional:dietary-supplements:1, ingredient-block:zinc-gluconate:ods-block:zinc-health-professional:dietary-supplements:2, ingredient-block:zinc-gluconate:ods-block:zinc-health-professional:dietary-supplements:3
Source attribution does not imply NIH or ODS endorsement of MEDucated.
Intake and dose reference information
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Populations needing caution
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Pregnancy and lactation
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Laboratory and test considerations
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Regulatory status
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Evidence limitations
Direct source evidence for this ingredient topic is not yet available in MEDucated.
Architecture readiness
Connected without overreaching
This identity can participate in future interaction and product-label models without creating an interaction conclusion or product score.Canonical resolution
Exact names and registered aliases can resolve to entity:ingredient:zinc-gluconate. Uncertain terms remain unresolved.
Identity mapping only
Future labels can preserve literal wording, quantity, unit, serving basis, order, and source provenance separately from this identity.